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Binding kinetics is a highly underappreciated optimization parameter.

Long residence times influence the in vivo efficacy of compounds and decouple pharmacodynamics from pharmacokinetics.

We have successfully pre-engineered scaffolds with desired binding kinetic signatures for a number of therapeutically relevant target classes, such as protein kinases, epigenetic enzymes, and protein–protein interaction targets.

Let us make binding kinetics a breakthrough parameter for your project!

Contact a Binding Kinetics Expert